Science. It Works. #9

Scientific peer review: an ineffective and unworthy institution by Les Hatton and Gregory Warr Given the entirely appropriate degree of respect that science has for data, the ongoing discussion of peer review is often surprisingly data-free and underlain by the implicit assumption that peer review – although in need of improvement – is indispensable. The …

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Science. It Works. #8

NOTE: the purpose of posts in the "Science. It Works." series is intentionally ambiguous Papers Based on Misidentified Cell Lines Top 32,000 Cell line misidentification is rampant throughout biomedical research, and a new analysis quantifies its impact on the scientific literature, finding more than 32,000 papers used lines with no known original stock. "In this …

Science. It Works. #7

Most scientists 'can't replicate studies by their peers' Science is facing a "reproducibility crisis" where more than two-thirds of researchers have tried and failed to reproduce another scientist's experiments, research suggests. This is frustrating clinicians and drug developers who want solid foundations of pre-clinical research to build upon. From his lab at the University of …

Science. It Works. #6

Bad science misled millions with chronic fatigue syndrome. Here’s how we fought back by Julie Rehmeyer If your doctor diagnoses you with chronic fatigue syndrome, you’ll probably get two pieces of advice: Go to a psychotherapist and get some exercise. Your doctor might tell you that either of those treatments will give you a 60 …

Science. It Works. #5

fMRI bugs could upend years of research A whole pile of “this is how your brain looks like” fMRI-based science has been potentially invalidated because someone finally got around to checking the data. The problem is simple: to get from a high-resolution magnetic resonance imaging scan of the brain to a scientific conclusion, the brain …

Science. It Works. #4

Opinion: Buried in bullshit Tom Farsides and Paul Sparks smell trouble. ... There is a worrying amount of outright fraud in psychology, even if it may be no more common than in other disciplines. Consider the roll call of those who have in recent years had high-status peer-reviewed papers retracted because of confirmed or suspected …

Science. It Works. #3

Scientific Regress by William A. Wilson The problem with ­science is that so much of it simply isn’t. Last summer, the Open Science Collaboration announced that it had tried to replicate one hundred published psychology experiments sampled from three of the most prestigious journals in the field. Scientific claims rest on the idea that experiments …